Data Center AMD

AMD Instinct MI300X

CDNA3 Architecture · 192GB HBM3 · OAM

VRAM
192GB
FP16
653.7
TDP
750W
Hardware Price
$18k
MSRP: $15k
Cloud from
$1.99/hr
1 providers
Cheapest at RunPod →

Quick Insights

Performance/Dollar
36.32 TFLOPS/$k
FP16 performance per $1000
VRAM/Dollar
10.7 GB/$k
VRAM per $1000
vs Data Center Average
+264% perf
FP16 TFLOPS comparison
Cloud Availability
1 providers
from $1.99/hr

Specifications

VRAM 192GB HBM3
Memory Bandwidth 5.3 TB/s
FP16 TFLOPS 653.7
Tensor TFLOPS -
FP32 TFLOPS 163.4
TDP 750W
Form Factor OAM
Architecture CDNA3
NVLink No
Release Date 2023-12

MI300X Price and Rental Notes

MI300X searches are mostly price and high-memory comparison intent. The core decision is whether 192GB HBM3 capacity offsets limited availability compared with NVIDIA H100 cloud ecosystems.

AMD MI300X price and cloud availability

MI300X is attractive for memory-bound LLM inference and training because 192GB VRAM can reduce model sharding. Compare its listed hourly cloud price against H100 and H200 options before choosing a stack.

When MI300X is the better value

MI300X becomes compelling when a workload needs very large memory per GPU and runs well on the available ROCm or provider-managed software environment.

Compatibility checks

Before migrating from NVIDIA, confirm framework support, container images, kernel versions, multi-GPU networking, and whether your model libraries are tested on MI300X.

Related: MI300X vs H100 PCIe Best GPUs for LLM training Cloud GPU pricing table

Buy vs Rent Analysis

Buy Hardware
$18k
  • One-time cost, unlimited usage
  • Full control over hardware
  • Electricity & cooling costs extra
  • Depreciation over 2-3 years
Best if using >9045 hours total
Rent Cloud GPU
$1.99/hr
  • Pay only for what you use
  • No upfront investment
  • Scale up/down instantly
  • No maintenance required
Best for <9045 hours or variable usage
Breakeven Point
9,045
hours of usage

At $1.99/hr cloud pricing, buying the hardware pays off after 9,045 hours (~377 days or 12.6 months of 24/7 usage).

Usage Monthly Cloud Cost Months to Breakeven
100 hrs/month $199.00 91 months
200 hrs/month $398.00 46 months
500 hrs/month $995.00 19 months

Cloud GPU Pricing

Rent AMD Instinct MI300X from 1 cloud providers. Prices shown per GPU per hour.

Provider Type Instance GPUs On-Demand Per GPU Spot Availability
RunPod gpu-cloud AMD Instinct MI300X OAM 1x $1.99/hr $1.99/hr Cheapest $1.49/hr (-25%) -
Best Spot Deal: RunPod offers spot pricing at $1.49/hr (25% off on-demand).

MI300X vs Alternatives

Compare AMD Instinct MI300X with similar GPUs from other brands.

GPU VRAM FP16 TFLOPS Bandwidth Hardware Price Cloud Price
MI300X Current 192GB 653.7 5.3 TB/s $18k - -
B200 NVIDIA 192GB (+0%) - 8.0 TB/s $45k (+150%) $3.75/hr Compare
B200 SXM6 NVIDIA 180GB (-6%) - - - $4.99/hr Compare
NVIDIA H200 NVL NVIDIA 143GB (-26%) - - - $3.39/hr Compare
H200 NVIDIA 141GB (-27%) 134.0 (-80%) 4.8 TB/s $38k (+111%) $2.30/hr Compare
GH200 NVIDIA 96GB (-50%) - - - $1.49/hr Compare

Best Use Cases for MI300X

🧠
LLM Training
4/5

AMD training option
⚡
AI Inference
4/5

High VRAM inference

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Frequently Asked Questions about MI300X

MI300X purchase and cloud prices vary by supplier and availability. Use this page to compare hardware assumptions, cloud hourly rates, and alternatives with similar high-memory profiles.

It can be cheaper for memory-heavy workloads if your software stack is compatible. For CUDA-first production systems, H100 may still reduce integration risk.

The AMD Instinct MI300X has a market price of approximately $18k (MSRP: $15k). Cloud rental starts at $1.99/hr. Prices may vary based on retailer, region, and availability.

Yes, the AMD Instinct MI300X with 192GB VRAM is suitable for many AI/ML workloads. It's particularly recommended for LLM Training. For large language models, you may need multiple GPUs or consider higher-VRAM options like A100 or H100.

The breakeven point is approximately 9,045 hours of usage. Buy if you'll use it more than this; rent for shorter projects or variable workloads. Cloud rental from RunPod starts at $1.99/hr.

With 192GB VRAM and 653.7 FP16 TFLOPS, the AMD Instinct MI300X can run: Large language models (7B-13B), Stable Diffusion XL, video AI, and professional 3D rendering.

The AMD Instinct MI300X offers 192GB VRAM and 653.7 FP16 performance at $18k. Compare with similar GPUs using our comparison tool above. Key factors: VRAM for model size, TFLOPS for speed, and price for budget.