RTX 4080 vs AMD Instinct MI100

Detailed comparison of specifications, performance, and pricing between NVIDIA GeForce RTX 4080 and AMD Instinct MI100

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Overall Winner
AMD Instinct MI100
Wins 4 of 7 categories
Performance Leader
AMD Instinct MI100
184.6 TFLOPS (+89%)
The AMD Instinct MI100 is 89% faster.

Difference Analysis

Metric
RTX 4080
Difference
AMD Instinct MI100
Tensor TFLOPS
97.5
-89%
184.6
VRAM
16GB
-100%
32GB
Memory Bandwidth
717 GB/s
-71%
1.2 TB/s
Hardware Price
$$900
=
-
Cloud Price/hr
$0.500
=
-

Full Specifications

Specification RTX 4080 AMD Instinct MI100
Brand NVIDIA AMD
Series Consumer Data Center
Architecture Ada Lovelace CDNA
VRAM 16GB 32GB
VRAM Type GDDR6X HBM2
Memory Bandwidth 717 GB/s 1.2 TB/s
FP16 TFLOPS 97.5 184.6
Tensor TFLOPS - 184.6
TDP 320W 300W
Form Factor PCIe -
Hardware Price $$900 -
Cloud Price (min) $0.500/hr -

Which Should You Choose?

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For AI Training

Large model training needs maximum VRAM and memory bandwidth.

Recommended: AMD Instinct MI100
32GB VRAM · 1.2 TB/s

For AI Inference

Inference prioritizes throughput and cost efficiency.

Recommended: AMD Instinct MI100
Best performance per dollar

RTX 4080 vs AMD Instinct MI100 FAQ

It depends on your use case. The AMD Instinct MI100 offers 89% better performance (184.6 vs 97.5 TFLOPS). For raw performance, choose AMD Instinct MI100. For value, consider your budget and workload requirements.

The AMD Instinct MI100 has more VRAM with 32GB compared to 16GB (100% more). More VRAM is crucial for training large models and running inference on bigger batch sizes.

For AI training, the AMD Instinct MI100 is generally better due to its larger VRAM (32GB). Large language models and deep learning workloads benefit significantly from more memory. However, if your models fit in 16GB, the cheaper option may be more cost-effective.

Price comparison requires both GPUs to have available pricing data. Check individual GPU pages for current market prices.

The AMD Instinct MI100 actually offers 89% better performance. An "upgrade" to RTX 4080 would be a downgrade in raw performance, though it may offer other benefits like lower power consumption or cost.