H100 PCIe vs AMD Instinct MI250X

Detailed comparison of specifications, performance, and pricing between NVIDIA H100 PCIe and AMD Instinct MI250X

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Overall Winner
H100 PCIe
Wins 2 of 7 categories
Performance Leader
H100 PCIe
1.5k TFLOPS (+98%)
The H100 PCIe is 98% faster.

Difference Analysis

Metric
H100 PCIe
Difference
AMD Instinct MI250X
Tensor TFLOPS
1.5k
+98%
766.0
VRAM
80GB
-60%
128GB
Memory Bandwidth
2.0 TB/s
-64%
3.3 TB/s
Hardware Price
$$28k
=
-
Cloud Price/hr
$2.39
=
-

Full Specifications

Specification H100 PCIe AMD Instinct MI250X
Brand NVIDIA AMD
Series Data Center Data Center
Architecture Hopper CDNA 2
VRAM 80GB 128GB
VRAM Type HBM2e HBM2E
Memory Bandwidth 2.0 TB/s 3.3 TB/s
FP16 TFLOPS 102.0 383.0
Tensor TFLOPS 1.5k 766.0
TDP 350W 560W
Form Factor PCIe -
Hardware Price $$28k -
Cloud Price (min) $2.39/hr -

Which Should You Choose?

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For AI Training

Large model training needs maximum VRAM and memory bandwidth.

Recommended: AMD Instinct MI250X
128GB VRAM · 3.3 TB/s

For AI Inference

Inference prioritizes throughput and cost efficiency.

Recommended: H100 PCIe
Best performance per dollar

H100 PCIe vs AMD Instinct MI250X FAQ

It depends on your use case. The H100 PCIe offers 98% better performance (1.5k vs 766.0 TFLOPS). For raw performance, choose H100 PCIe. For value, consider your budget and workload requirements.

The AMD Instinct MI250X has more VRAM with 128GB compared to 80GB (60% more). More VRAM is crucial for training large models and running inference on bigger batch sizes.

For AI training, the AMD Instinct MI250X is generally better due to its larger VRAM (128GB). Large language models and deep learning workloads benefit significantly from more memory. However, if your models fit in 80GB, the cheaper option may be more cost-effective.

Price comparison requires both GPUs to have available pricing data. Check individual GPU pages for current market prices.

Upgrading to H100 PCIe would give you 98% more performance and similar VRAM. Consider if your workloads are bottlenecked by current GPU capabilities.