H100 NVL vs AMD Instinct MI250

Detailed comparison of specifications, performance, and pricing between NVIDIA H100 NVL and AMD Instinct MI250

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Overall Winner
H100 NVL
Wins 3 of 7 categories
Performance Leader
H100 NVL
2.0k TFLOPS (+173%)
The H100 NVL is 173% faster.

Difference Analysis

Metric
H100 NVL
Difference
AMD Instinct MI250
Tensor TFLOPS
2.0k
+173%
724.0
VRAM
94GB
-36%
128GB
Memory Bandwidth
3.9 TB/s
+19%
3.3 TB/s
Hardware Price
$$35k
=
-
Cloud Price/hr
$1.38
=
-

Full Specifications

Specification H100 NVL AMD Instinct MI250
Brand NVIDIA AMD
Series Data Center Data Center
Architecture Hopper CDNA 2
VRAM 94GB 128GB
VRAM Type HBM3 HBM2E
Memory Bandwidth 3.9 TB/s 3.3 TB/s
FP16 TFLOPS 134.0 362.0
Tensor TFLOPS 2.0k 724.0
TDP 400W 500W
Form Factor NVL -
Hardware Price $$35k -
Cloud Price (min) $1.38/hr -

Which Should You Choose?

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For AI Training

Large model training needs maximum VRAM and memory bandwidth.

Recommended: AMD Instinct MI250
128GB VRAM · 3.3 TB/s

For AI Inference

Inference prioritizes throughput and cost efficiency.

Recommended: H100 NVL
Best performance per dollar

H100 NVL vs AMD Instinct MI250 FAQ

It depends on your use case. The H100 NVL offers 173% better performance (2.0k vs 724.0 TFLOPS). For raw performance, choose H100 NVL. For value, consider your budget and workload requirements.

The AMD Instinct MI250 has more VRAM with 128GB compared to 94GB (36% more). More VRAM is crucial for training large models and running inference on bigger batch sizes.

For AI training, the AMD Instinct MI250 is generally better due to its larger VRAM (128GB). Large language models and deep learning workloads benefit significantly from more memory. However, if your models fit in 94GB, the cheaper option may be more cost-effective.

Price comparison requires both GPUs to have available pricing data. Check individual GPU pages for current market prices.

Upgrading to H100 NVL would give you 173% more performance and similar VRAM. Consider if your workloads are bottlenecked by current GPU capabilities.